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Methods and Findings
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Volume 24, Suppl. B, September 2002, Pages 1-53

CDP-Choline: Update and Review of its Pharmacology and Clinical Use

INTRODUCTION
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PHARMACOLOGICAL ACTIONS
   Traumatic injuries and experimental cerebral edema
   Hypoxia and cerebral ischemia
   Synaptic transmission and neurotransmitter levels
   Learning performance, memory and cerebral aging
   Experimental abstinence syndrome and intoxications
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TOXICITY
   Acute toxicity
   Subacute toxicity
   Chronic toxicity
   Teratogenicity
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PHARMACOKINETICS
   lasma concentration curves bioavailability
  Tissue diffusion and distribution
      Transport and metabolism
   Elimination pathway and kinetics
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CLINICAL EXPERIENCE
   Head injuries and sequelae
   Acute cerebral vascular disease and sequelae
   Cognitive disorders
   Other clinical experiences
      Parkinson's disease
      Alcoholism and drug addiction
      Amblyopia and glaucoma
   Safety
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CONCLUSIONS
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REFERENCES
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