Quick Search 
Drug News & Perspectives
Register or sign in

Drug News Perspect 2006, 19(6): 317
ISSN 0214-0934
Copyright 2006 Clarivate Analytics
CCC: 0214-0934


The field of siRNA-based theraeutics is rapidly progressing with the development of chemically modified siRNAs and a variety of novel delivery strategies.

RNA Interference for the Treatment of Cancer

by Lisa N. Putral, Wenyi Gu and Nigel A.J. McMillan


RNA interference (RNAi) is the latest new technology in the field of genetic medicine in which specific genes can be turned off, or silenced, so as to affect a therapeutic outcome. It can be highly specific, works in the nanomolar range and is far more effective than the antisense approaches popular 10-15 years ago. Here we review the field and explore the potential role of RNAi in cancer therapy, highlighting recent progress and examining the hurdles that must be overcome before this promising technology is ready for clinical use. © 2006 Prous Science. All rights reserved.

Full Text: HTMLPDF 

© Clarivate Analytics. All rights reserved.
Copyright NoticeTerms of UsePrivacy StatementCookie Policy